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DrugBank Online Database for Drug and Drug Target Info
WEBEmpower better health decisions. Enhance your clinical software and transform healthcare delivery with evidence-based, structured drug information. Easily integrate our Clinical …
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Metformin: Uses, Interactions, Mechanism of Action DrugBank …
WEBGeneric Name Metformin DrugBank Accession Number DB00331 Background. Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. 23,14 Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing …
Propranolol: Uses, Interactions, Mechanism of Action DrugBank …
WEBGeneric Name Propranolol DrugBank Accession Number DB00571 Background. Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. 9 Propranolol is used to treat a number of conditions but most commonly is used for hypertension. …
Magnesium oxide: Uses, Interactions, Mechanism of …
WEBMagnesium oxide is a compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and …
Category: Supplements Go Health
Diosmin: Uses, Interactions, Mechanism of Action DrugBank Online
WEBDiosmin is a citrus flavonoid medication used to support vascular health. Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. 6. Diosmin is a bioflavonoid …
Lactulose: Uses, Interactions, Mechanism of Action DrugBank …
WEBLactulose. Lactulose is a disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).
Hydrochlorothiazide: Uses, Interactions, Mechanism of Action
WEBAbsorption. An oral dose of hydrochlorothiazide is 65-75% bioavailable, with a T max of 1-5 hours, and a C max of 70-490ng/mL following doses of 12.5-100mg. 10,11 When taken with a meal, bioavailability is 10% lower, C max is 20% lower, and T max increases from 1.6 to 2.9 hours. 11. Volume of distribution. The volume of distribution varies widely from one …
Narrow Therapeutic Index Drugs DrugBank Online
WEBNarrow therapeutic index (NTI) drugs are defined as those drugs where small differences in dose or blood concentration may lead to dose and blood concentration dependent, serious therapeutic failures or adverse drug reactions. Serious events are those which are persistent, irreversible, slowly reversible, or life-threatening, possibly resulting
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