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Three US Food and Drug Administration–approved therapies for …

WebChronic graft-versus-host disease (cGVHD) is a major immunologic complication of allogeneic hematopoietic cell transplantation. cGVHD involves multiple …

Actived: 7 days ago

URL: https://ashpublications.org/blood/article/139/11/1642/483700/Three-US-Food-and-Drug-Administration-approved

Treatment of bleeding complications in patients on anticoagulant

WebBleeding is the dominant adverse event of treatment with any anticoagulant. 1 Major bleeding complications such as intracranial hemorrhage (ICH) or massive …

Category: Health Go Health

Non-Myeloablative Lymphodepleting Conditioning in Patients …

WebA total of 165 patients (male: 100, female: 65) were enrolled across seven studies from 1991-2010, all with metastatic melanoma except 13 patients with epithelial …

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How I treat AML incorporating the updated classifications and

WebTogether, the updated 2022 ELN and 2021 MRD guidelines, in addition to the fifth edition of the WHO and ICC classifications of myeloid neoplasms 1, 2, 5, 7 (Tables 1 …

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Preventing infections in children and adults with asplenia

WebAn estimated 1 million people in the United States have functional or anatomic asplenia or hyposplenia. Infectious complications due to encapsulated organisms such …

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American Society of Hematology 2020 guidelines for sickle cell …

WebThree of 19 recommendations immediately impact clinical care. These recommendations include: use of transcranial Doppler ultrasound screening and …

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New Health Care Policies in FY 2023 ASH Clinical News

WebThe legislation covers a variety of health care policies including Medicare, Medicaid, telehealth, and pandemic preparedness. One change enacted by the …

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How I assess and manage the risk of bleeding in patients treated …

WebThe most feared complication of anticoagulant treatment of venous thromboembolism (VTE) is major bleeding, which occurs up to a rate of 7.22 per 100 …

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American Society of Hematology 2018 guidelines for management …

WebVenous thromboembolism (VTE) is the third most common cardiovascular diagnosis, with an incidence rate of ∼1 in 1000 annually in middle age and increasing to …

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A program of transition to adult care for sickle cell disease

WebAmong individuals with SCD, a rise in mortality occurs in the early young adulthood years (ages 20 to 24 years) (), coinciding with the period in which they leave …

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Evidence-based management of pregnant women with sickle cell …

WebThis article describes how SCD is managed during pregnancy in the Western World, particularly in the United Kingdom. It aims to cover preconception screening and …

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Sickle Cell Disease in 2023: Laying the Foundation for Future

WebNovel, alternative gene editing approaches for SCD are also in various stages of clinical development, portending more curative-intent options in the future. 3, 4 …

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Patient blood management as the standard of care

WebBlood transfusion is one of the most common hospital procedures in developed countries, such as the United States and the United Kingdom. 2 Over 11.3 …

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How we evaluate and treat neutropenia in adults Blood

WebAbstract. Isolated neutropenia is a common clinical problem seen by primary care physicians and hematologists. The evaluation of neutropenia is dictated by the …

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Epidemiology and treatment of priapism in sickle cell disease

WebSickle cell disease (SCD) is associated with priapism, a persistent painful erection occurring with or without sexual desire. 1,2 Priapism-related pain is a cardinal …

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The relationship between blood groups and disease

WebThe molecular basis of the ABO blood group system was elucidated in 1990. 7 The gene encodes a glycosyltransferase, which transfers N-acetyl D-galactosamine …

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How to evaluate the patient with a suspected mast cell disorder …

WebMast cell disorders include mastocytosis and mast cell activation syndromes. Mastocytosis is a rare clonal disorder of the mast cell, driven by KIT D816V mutation in …

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Gynecologic Conditions and Anemia: What Can We Do About Iron …

WebHMB is underdiagnosed and is estimated to affect 18 to 38 percent of women of reproductive age, and may be higher in perimenopausal individuals. 4 Causes include …

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Hazardous to Your Health: Violence in the Health-Care Workplace

WebAn Expansive, Expensive Problem. Workers in the medical field, compared with other workplace settings, are particularly vulnerable to violence. According to data collected by …

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Long-term outcomes among adults with Langerhans cell …

WebLangerhans cell histiocytosis (LCH) is a rare histiocytic disorder, with manifestations ranging from indolent unifocal disease to multisystem disease, causing …

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