Atlasgeneticsoncology.org

Atlas of Genetics and Cytogenetics in Oncology and …

WebA special thanks is expressed to Jean-Loup Huret, father and editor in chief since 1997. The Atlas of Genetics and Cytogenetics in Oncology and Haematology gives reviews on …

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URL: https://www.atlasgeneticsoncology.org/

Angiogenic factors and cancer therapy

WebThe original idea of blocking tumor-derived angiogenic factors for cancer therapy was raised by Dr. Judah Folkman. In his conceptual paper, Folkman wrote "One approach to the …

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Mixed cellularity classical Hodgkin lymphoma (MCcHL)

WebMC is a subtype of cHL characterized by diagnostic HRS cells in a mixed inflammatory back-ground without sclerosis. Mononuclear Hodgkin cells can be present. The mixed cellular …

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An Introduction to Chromosomal Aberrations

WebAn Introduction to Chromosomal Aberrations. Introduction. Visible changes to chromosome structure and morphology have played a very important part as indicators of genetic …

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Classification of Hodgkin lymphoma over years

WebHistologic classification of Hodgkin lymphoma (HL) evolved through different systems, starting from the modern histologic classifications by Jackson and Parker in …

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LTA (Lymphotoxin-A)

WebThe human TNFb protein contains 205 amino acids. The soluble form of TNFb is usually a homotrimer with a relative molecular mass of 60 to 70 kDa, whereas the …

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Nodular sclerosis classical Hodgkin lymphoma (NScHL)

WebClassical Hodgkin lymphoma is a distinct neoplastic entity with heterogeneous epidemiological features. It accounts for approximately 10% of all malignant lymphomas …

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Clathrin Mediated Endocytosis and its Role in Viral Entry

WebThe process of CME can be separated into several steps, which include: (1) the nucleation of a clathrin coated pit (CCP); (2) cargo capture in coated pits; (3) curvature induction …

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Wiskott-Aldrich Syndrome (WAS)

WebWiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation. New insights into the biology of …

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del(5q) in myeloid neoplasms

WebAdditional anomalies. By definition, an interstitial deletion of 5q must be the sole abnormality for 5q- syndrome. However, 5q deletion can be seen with other …

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+7 or trisomy 7 (solely)

WebTrisomy 7 is a common finding in benign and malignant solid tumors, in several non-neoplastic lesions (for example, osteoarthritis and rheumatoid arthritis), and …

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Atlas of Genetics and Cytogenetics in Oncology and Haematology

WebAtlas of Genetics and Cytogenetics in Oncology and Haematology

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Mixed phenotype acute leukemia (MPAL)

WebMixed phenotype acute leukemia is a rare disease and comprises 2-5% of all acute leukemias. A simpler diagnostic algorithm is now used to define mixed phenotype acute …

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KANSL1/ARL17A (17q21)

WebTitle. Citations. 30914738. 2019. Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma. 11. 28881586. 2017. Identification of KANSARL …

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t(1;19)(q22;p13.2) MEF2D/HNRNPUL1

WebProtein description. HNRNPUL1 is a nuclear RNA-binding protein which belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) family. HNRNPUL1 acts as a basic …

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Inv(3)(q21q26) GATA2::MECOM t(3;3)(q21;q26) GATA2::MECOM …

WebInv(3) and t(3;3) have been documented in de novo AML (in all FAB subtypes except M3), therapy related AML (t-AML), MDS, CML, more often in accelerated phase or blast crisis, …

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