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Vitamin D, gut microbiota, and radiation-related …

WebRadiation resistance is a serious issue in radiotherapy. Increasing evidence indicates that the human gut microbiome plays a role in the development of radiation …

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URL: https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1499-y

Gut microbiota influence tumor development and Alter …

WebHuman intestines harbor approximately 3.8 × 10 13 microorganisms that maintain the physiology and health of the host by influencing basic functions, such as …

Category: Health Go Health

Oral mucositis: the hidden side of cancer therapy Journal …

WebInflammation response of epithelial mucosa to chemo- radiotherapy cytotoxic effects leads to mucositis, a painful side effect of antineoplastic treatments. About 40% of …

Category: Health Go Health

Current and future therapeutic strategies for high-grade …

WebTargeted therapies, including small molecule inhibitors directed against aberrant kinase signaling and chromatin regulators, are emerging treatment options for …

Category: Health Go Health

Emerging therapies for glioblastoma: current state and …

WebGliomas account for almost 30% of primary brain tumors and 80% of all malignant ones. Based on their histopathological features, gliomas are traditionally …

Category: Health Go Health

Health-related quality of life in breast cancer patients: A

WebHealth-related quality of life is now considered an important endpoint in cancer clinical trials. It has been shown that assessing quality of life in cancer patients …

Category: Cancer Go Health

Clinical development of targeted and immune based anti …

WebCancer is currently the second leading cause of death globally and is expected to be responsible for approximately 9.6 million deaths in 2018. With an …

Category: Cancer Go Health

Apoptosis in cancer: from pathogenesis to treatment

WebApoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. It is also one of the most studied topics among …

Category: Health Go Health

The world’s first digital cell twin in cancer …

WebThe introduction of functional in-silico models, in addition to in-vivo tumor models, opens up new and unlimited possibilities in cancer research and drug …

Category: Cancer Go Health

Iron and leukemia: new insights for future treatments

WebIron, an indispensable element for life, is involved in all kinds of important physiological activities. Iron promotes cell growth and proliferation, but it also causes …

Category: Health Go Health

Targeting hypoxia in tumor: a new promising therapeutic strategy

WebLow oxygen condition (hypoxia) is considered a hallmark of rapidly growing solid tumors. The presence of hypoxia renders tumor cells resistant to conventional …

Category: Health Go Health

Unveiling the gastric microbiota: implications for gastric

WebHigh-throughput sequencing has ushered in a paradigm shift in gastric microbiota, breaking the stereotype that the stomach is hostile to microorganisms …

Category: Health Go Health

Precision medicine applied to metastatic colorectal cancer using …

WebBackground Patients with colorectal metastatic disease have a poor prognosis, limited therapeutic options, and frequent development of resistance. …

Category: Health Go Health

Disulfidptosis: a new form of programmed cell death

WebDisulfides are relatively stable products that maintain the secondary, tertiary, and quaternary structures of proteins by acting as inter- and intra-subunit cross-links; …

Category: Health Go Health

Modulating ferroptosis sensitivity: environmental and cellular …

WebFerroptosis, a novel form of cell death triggered by iron-dependent phospholipid peroxidation, presents significant therapeutic potential across diverse …

Category: Health Go Health

GPR65 sensing tumor-derived lactate induces HMGB1 release …

WebGlioma, is the most common and aggressive primary intracranial tumors, accounting for over 40% of primary intracranial tumors [].According to the World Health …

Category: Health Go Health

Acute myeloid leukemia: from NGS, through scRNA-seq, to CAR-T.

WebAcute myeloid leukemia (AML) is a malignant blood cancer with marked cellular heterogeneity due to altered maturation and differentiation of myeloid blasts, the …

Category: Cancer Go Health

Exploring the interaction between extracellular matrix components …

WebIn vitro models are necessary to study the pathophysiology of the disease and the development of effective, tailored treatment methods owing to the complexity …

Category: Health Go Health