Jneurosci.org

Journal of Neuroscience

WebPictured is an average MRI image of the group-wide volume increases to the hippocampus of middle-aged beagles over three years. Jessica Noche et al. tested the effects of long …

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The Next 50 Years of Neuroscience Journal of …

WebIn combination, advances made by basic, translational, and clinical neuroscience research in the next 50 years have great potential for lasting improvements …

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Hallucinogens in Mental Health: Preclinical and Clinical …

WebA revamped interest in the study of hallucinogens has recently emerged, especially with regard to their potential application in the treatment of psychiatric …

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Revisiting the Stress Concept: Implications for Affective …

WebThe impact of this overload is deleterious to brain health, and it results in vulnerability to a range of brain disorders, including major depression and cognitive …

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Gut Microbes and the Brain: Paradigm Shift in Neuroscience

WebThe discovery of the size and complexity of the human microbiome has resulted in an ongoing reevaluation of many concepts of health and disease, including …

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Cannabis and the Developing Brain: Insights into Its Long …

WebThe recent shift in sociopolitical debates and growing liberalization of cannabis use across the globe has raised concern regarding its impact on vulnerable …

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Estrogen, Menopause, and the Aging Brain: How Basic …

WebThis work was supported by National Institute of Mental Health Intramural Research Program (P.J.S.) and Grant MH67159 (R.D.B.), National Institute of Aging …

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Cumulative Effects of Resting-State Connectivity Across …

WebIdentification of replicable neuroimaging correlates of attention-deficit hyperactivity disorder (ADHD) has been hindered by small sample sizes, small effects, …

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Making Connections: Neurodevelopmental Changes in …

WebAbstract. Adverse childhood experiences have been linked to detrimental mental health outcomes in adulthood. This study investigates a potential …

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The β-Secretase Enzyme BACE in Health and Alzheimer's …

WebThe β-amyloid (Aβ) peptide is the major constituent of amyloid plaques in Alzheimer's disease (AD) brain and is likely to play a central role in the pathogenesis of …

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Advances in Enteric Neurobiology: The “Brain” in the Gut in Health …

WebThe enteric nervous system (ENS) is a large, complex division of the peripheral nervous system that regulates many digestive, immune, hormonal, and …

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Impact and Role of Hypothalamic Corticotropin Releasing …

WebWorldwide, alcohol use and abuse are a leading risk of mortality, causing 5.3% of all deaths ([World Health Organization, 2022][1]). The endocrine stress system, …

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Nutrition, Brain Aging, and Neurodegeneration

WebThe onset of age-related neurodegenerative diseases superimposed on a declining nervous system could enhance the motor and cognitive behavioral deficits that …

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The Role of Transposable Elements in Health and Diseases of the …

WebFirst discovered in maize by Barbara McClintock in the 1940s, transposable elements (TEs) are DNA sequences that in some cases have the ability to move along …

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Physical Exercise Prevents Stress-Induced Activation of Granule …

WebPhysical exercise is known to reduce anxiety. The ventral hippocampus has been linked to anxiety regulation but the effects of running on this subregion of the …

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Toward an Anti-Racist Approach to Biomedical and Neuroscience …

WebRacism is a threat to public health. Race is a sociopolitical construct that has been used for generations to create disparities in educational access, housing …

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Exercise, Energy Intake, Glucose Homeostasis, and the Brain

WebHere we summarize topics covered in an SFN symposium that considered how and why exercise and energy intake affect neuroplasticity and, conversely, how the …

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Music and Brain Circuitry: Strategies for Strengthening Evidence …

WebThe neuroscience of music and music-based interventions (MBIs) is a fascinating but challenging research field. While music is a ubiquitous component of …

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Focusing Attention on the Health Aspects of Foods Changes Value …

WebNote that all subjects reported their decisions using the entire decision scale. Third, the postscanning health and taste ratings provide independent measures of the …

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Estrogen Shapes Dopamine-Dependent Cognitive Processes: …

WebThe prefrontal cortex (PFC) is exquisitely sensitive to its neurochemical environment. Minor fluctuations in cortical dopamine (DA) can profoundly alter working …

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Control of Selective mRNA Translation in Neuronal Subcellular

WebMethodologies for the isolation of subcellular compartments and detection of local translation. Several techniques have been developed to isolate neuronal subcellular …

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Circuit-wide gene network analysis reveals sex-specific roles for

WebCocaine use disorder is a significant public health issue without an effective pharmacological treatment. Successful treatments are hindered in part by an incomplete …

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