Can Gene Variants Cause Health Problems
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Gene–environment interactions and their impact on human health
(Just Now) WebWe then examine how these two factors can work together to increase disease risk. Fig. 1: Gene × environment (G × E) interactions involve synergy between …
https://www.nature.com/articles/s41435-022-00192-6
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Genetic variation across and within individuals - Nature
(Just Now) WebGenetic variation across and within individuals is a dynamic mosaic of germline and somatic variants that can influence one another to shape health and …
https://www.nature.com/articles/s41576-024-00709-x
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Study Identifies the Genes That Increase Your Risk of Depression
(7 days ago) WebScientists are increasingly looking toward genetics. A new study identified 178 gene locations linked to major depression—77 more than scientists had previously …
https://www.verywellhealth.com/study-identifies-the-genetic-roots-of-depression-5188815
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Five steps to connect genetic risk variants to disease - Nature
(Just Now) WebOur Variant-to-Gene-to-Program (V2G2P) approach consists of five steps. In step one, we choose a cell type relevant to disease. In steps two and three, we use …
https://www.nature.com/articles/d41586-024-00061-4
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Clinical Interpretation and Management of Genetic Variants
(3 days ago) WebGenetic variants are major determinants of susceptibility to disease, response to therapy, and clinical outcomes. Advances in the short-read sequencing …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591931/
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Genetics and Health - Genes, Behavior, and the Social Environment
(4 days ago) Web3. Genetics and Health. Although there are many possible causes of human disease, family history is often one of the strongest risk factors for common disease …
https://www.ncbi.nlm.nih.gov/books/NBK19932/
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Genetic Variation, Comparative Genomics, and the Diagnosis of …
(3 days ago) WebThe discovery of mutations associated with human genetic disease is an exercise in comparative genomics (see Glossary). Although there are many different …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681822/
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Study identifies new genetic variants that cause developmental
(2 days ago) WebThe paper, published in the American Journal of Human Genetics, identified seven variants that were previously unknown that cause developmental disorders, and …
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Newly discovered genetic variant that causes Parkinson’s disease
(4 days ago) WebIn the mid-1990s, researchers started looking into whether genetic differences between people with or without Parkinson’s might identify specific genes or …
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Genetic tests unexpectedly find genes linked to heart disease — …
(2 days ago) WebVariants associated with cardiovascular disease risk are often found “incidentally” when people undergo genetic testing for non-cardiac reasons, including …
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Study Suggests Genetics as a Cause, Not Just a Risk, for Some …
(4 days ago) WebPeople with two copies of the gene variant APOE4 are almost certain to get Alzheimer’s, say researchers, who proposed a framework under which such patients …
https://www.nytimes.com/2024/05/06/health/alzheimers-cause-gene-apoe4.html
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A Genetic Mutation That Can Affect Mental & Physical Health
(6 days ago) WebKey points. Mental health issues associated with a MTHFR mutation include depression, bipolar disorder, schizophrenia, and ADHD. Up to 40% of the population …
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Tempted to have genetic testing? First ask why - Harvard Health
(4 days ago) WebAmong adults who have the most common genetic variants that cause it, heart attack or sudden cardiac death may occur in middle age. Children who have a …
https://www.health.harvard.edu/blog/tempted-to-have-genetic-testing-first-ask-why-202108172571
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First glimpse of how genes may cause mental health problems
(5 days ago) WebFirst glimpse of how genes may cause mental health problems. Schizophrenia, bipolar disorder and autism seem to have some similar effects on the …
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Can DNA variants that cause disease be distinguished from those …
(7 days ago) Web“One problem we are facing is that there are too many DNA variants or mutations of unknown effects that can be observed from a random genome, yet the vast …
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Determining genetic causes for sudden cardiac death
(9 days ago) WebCertain genetic variants can cause irregular heart rhythms, called arrythmias, and can affect how well the heart is able to pump blood to the rest of the body. The likelihood …
https://medschool.duke.edu/blog/determining-genetic-causes-sudden-cardiac-death
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MTHFR Gene Mutations and Disease - Verywell Health
(2 days ago) WebMore than 40 MTHFR genetic mutations are linked to homocystinuria, a condition where the amino acid builds up in the bloodstream. Homocystinuria is …
https://www.verywellhealth.com/mthfr-gene-mutations-disease-risk-3232709
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A gene long thought to just raise the risk for Alzheimer's may …
(1 days ago) WebA long-feared gene appears to do more than raise people’s risk of Alzheimer’s: Inheriting two copies can cause the mind-robbing disease, according to …
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